| 15. Jornada | 05.12.2021 | RKC Waalwijk | - | NEC Nijmegen | 2:1 |  |
|||
| 16. Jornada | 12.12.2021 | FC Twente | - | RKC Waalwijk | 2:1 | ||||
| 18. Jornada | 23.12.2021 | Sparta Rotterdam | - | RKC Waalwijk | 1:1 | ||||
| 20. Jornada | 23.01.2022 | RKC Waalwijk | - | Fortuna Sittard | 2:1 | ||||
| 21. Jornada | 06.02.2022 | Willem II | - | RKC Waalwijk | 3:1 | ||||
| 24. Jornada | 25.02.2022 | RKC Waalwijk | - | FC Twente | 1:2 | ||||
| 25. Jornada | 06.03.2022 | AFC Ajax | - | RKC Waalwijk | 3:2 | ||||
| 26. Jornada | 12.03.2022 | RKC Waalwijk | - | sc Heerenveen | 0:0 |  |
|||
| 28. Jornada | 02.04.2022 | RKC Waalwijk | - | FC Utrecht | 1:1 | ||||
| 30. Jornada | 23.04.2022 | RKC Waalwijk | - | PEC Zwolle | 0:2 | ||||
| 33. Jornada | 11.05.2022 | RKC Waalwijk | - | Heracles Almelo | 2:0 | ||||
| 34. Jornada | 15.05.2022 | AZ Alkmaar | - | RKC Waalwijk | 1:3 | |
Países Bajos