| 1. Jornada | 08.07.2022 | Deportivo Pereira | - | Alianza Petrolera | 1:2 | ||||
| 3. Jornada | 17.07.2022 | Envigado FC | - | Alianza Petrolera | 2:2 |  |
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| 4. Jornada | 23.07.2022 | Alianza Petrolera | - | Atlético Bucaramanga | 3:1 | |
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| 5. Jornada | 30.07.2022 | Jaguares de Córdoba | - | Alianza Petrolera | 2:1 | ||||
| 6. Jornada | 07.08.2022 | Alianza Petrolera | - | Atlético Nacional | 0:2 | |
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| 7. Jornada | 13.08.2022 | Cortuluá | - | Alianza Petrolera | 0:2 | |
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| 8. Jornada | 20.08.2022 | Alianza Petrolera | - | Deportivo Cali | 4:4 | ||||
| 9. Jornada | 28.08.2022 | Alianza Petrolera | - | Deportivo Pasto | 0:0 | ||||
| 10. Jornada | 03.09.2022 | Atlético Bucaramanga | - | Alianza Petrolera | 3:1 | |
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| 12. Jornada | 17.09.2022 | Alianza Petrolera | - | La Equidad | 1:2 | ||||
| 13. Jornada | 22.09.2022 | Patriotas FC | - | Alianza Petrolera | 0:0 | ||||
| 14. Jornada | 26.09.2022 | Alianza Petrolera | - | Atlético Junior | 0:1 | |
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| 15. Jornada | 01.10.2022 | Independiente Medellín | - | Alianza Petrolera | 3:1 | ||||
| 16. Jornada | 11.10.2022 | Alianza Petrolera | - | Santa Fe | 4:0 | ||||
| 19. Jornada | 24.10.2022 | Once Caldas | - | Alianza Petrolera | 1:1 | ||||
| 20. Jornada | 30.10.2022 | Alianza Petrolera | - | Millonarios | 2:4 |
Colombia