| 1. Jornada | 13.08.2021 | Gudja United | - | Sirens FC | 0:1 | ||||
| 4. Jornada | 19.09.2021 | Sliema Wanderers | - | Gudja United | 2:3 |  |
|||
| 5. Jornada | 25.09.2021 | Gudja United | - | Valletta FC | 2:0 | |
|||
| 6. Jornada | 16.10.2021 | Birkirkara FC | - | Gudja United | 2:0 | ||||
| 9. Jornada | 20.11.2021 | Gudja United | - | Floriana FC | 0:1 | ||||
| 10. Jornada | 28.11.2021 | Gżira United | - | Gudja United | 3:2 | ||||
| 11. Jornada | 04.12.2021 | Mosta FC | - | Gudja United | 0:3 | ||||
| 12. Jornada | 13.12.2021 | Sirens FC | - | Gudja United | 0:0 |
Ucrania