| 13. Jornada | 02.04.2022 | UANL Tigres [Sub 16] | - | Atlético San Luis [Sub 16] | 2:1 | ||||
| 14. Jornada | 05.04.2022 | Atlético San Luis [Sub 16] | - | Club Tijuana [Sub 16] | 3:1 | ||||
| 16. Jornada | 23.04.2022 | Mazatlán FC [Sub 16] | - | Atlético San Luis [Sub 16] | 2:1 | ||||
| 18. Jornada | 07.05.2022 | Atlas Guadalajara [Sub 16] | - | Atlético San Luis [Sub 16] | 4:2 |
México