| 2. Jornada | 01.05.2021 | Phoenix Rising | - | San Diego Loyal | 4:1 | ||||
| 2. Jornada | 07.05.2021 | Rio Grande Valley FC | - | San Diego Loyal | 1:0 | ||||
| 2. Jornada | 14.05.2021 | Tacoma Defiance | - | San Diego Loyal | 3:1 |  |
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| 2. Jornada | 23.05.2021 | Louisville City FC | - | San Diego Loyal | 2:1 | ||||
| 2. Jornada | 30.05.2021 | San Diego Loyal | - | Las Vegas Lights FC | 2:1 | ||||
| 3. Jornada | 06.06.2021 | Phoenix Rising | - | San Diego Loyal | 2:2 | ||||
| 3. Jornada | 10.06.2021 | Orange County SC | - | San Diego Loyal | 1:1 | |
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| 3. Jornada | 13.06.2021 | San Diego Loyal | - | Los Angeles Galaxy II | 2:1 |
Francia