| 3. Jornada | 01.02.2020 | 12 de Octubre de Itauguá | - | Guaraní | 1:3 | ||||
| 4. Jornada | 09.02.2020 | Guaraní | - | Club Olimpia | 0:3 | ||||
| 5. Jornada | 16.02.2020 | Club Nacional | - | Guaraní | 1:2 | ||||
| 7. Jornada | 02.03.2020 | Sportivo Luqueño | - | Guaraní | 0:3 | ||||
| 11. Jornada | 02.08.2020 | Libertad | - | Guaraní | 1:3 | ||||
| 6. Jornada | 06.08.2020 | Guaraní | - | River Plate | 3:0 | ||||
| 15. Jornada | 21.08.2020 | Club Olimpia | - | Guaraní | 1:2 | ||||
| 17. Jornada | 29.08.2020 | River Plate | - | Guaraní | 1:0 |  |
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| 20. Jornada | 20.09.2020 | Guaraní | - | Guaireña FC | 0:0 | ||||
| 21. Jornada | 28.09.2020 | General Díaz | - | Guaraní | 0:1 | ||||
| 22. Jornada | 05.10.2020 | Guaraní | - | Libertad | 1:1 |
Paraguay