| 2. Jornada | 17.07.2021 | FK Orenburg | - | Metallurg Lipetsk | 4:0 | ||||
| 3. Jornada | 24.07.2021 | Baltika Kaliningrad | - | FK Orenburg | 1:1 | ||||
| 4. Jornada | 31.07.2021 | FK Orenburg | - | Fakel Voronezh | 0:2 | ||||
| 27. Jornada | 12.03.2022 | Rotor Volgograd | - | FK Orenburg | 0:3 |  |
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| 28. Jornada | 19.03.2022 | FK Orenburg | - | FK Kamaz | 2:0 | ||||
| 29. Jornada | 26.03.2022 | FK Krasnodar 2 | - | FK Orenburg | 5:2 | |
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| 30. Jornada | 02.04.2022 | FK Orenburg | - | Torpedo Moskva | 1:0 | ||||
| 31. Jornada | 06.04.2022 | Enisey Krasnoyarsk | - | FK Orenburg | 1:2 | ||||
| 32. Jornada | 10.04.2022 | FK Orenburg | - | Kuban Krasnodar | 1:3 | ||||
| 33. Jornada | 17.04.2022 | Spartak Moskva 2 | - | FK Orenburg | 2:3 |  |
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| 34. Jornada | 24.04.2022 | FK Orenburg | - | Alania Vladikavkaz | 0:0 | ||||
| 35. Jornada | 30.04.2022 | Tekstilshchik Ivanovo | - | FK Orenburg | 2:5 | ||||
| 36. Jornada | 07.05.2022 | FK Orenburg | - | Olimp-Dolgoprudny | 2:2 | ||||
| 37. Jornada | 15.05.2022 | SKA-Khabarovsk | - | FK Orenburg | 1:0 | ||||
| 38. Jornada | 21.05.2022 | Volgar Astrakhan | - | FK Orenburg | 2:2 |
Rusia