 |
 |
| Cuartos de final | ||||||
|---|---|---|---|---|---|---|
| 04.05.2022 | 17:00 | CF Pachuca | - | Atlas Guadalajara | 0:2 (0:1) | |
| 17:00 | Pumas UNAM | - | CF América | 3:0 (1:0) | ||
| 05.05.2022 | 18:15 | Deportivo Guadalajara | - | Santos Laguna | 4:1 (3:1) | |
| 21:45 | Club Tijuana | - | Club León | 3:2 (2:2) | ||
| 07.05.2022 | 16:00 | Atlas Guadalajara | - | CF Pachuca | 3:2 (2:0) | |
| 18:30 | CF América | - | Pumas UNAM | 2:1 (2:0) | ||
| 08.05.2022 | 17:00 | Santos Laguna | - | Deportivo Guadalajara | 4:1 (1:0) | |
| 18:30 | Club León | - | Club Tijuana | 0:3 (0:1) | ||
| Semifinales | ||||||
| 11.05.2022 | 17:00 | Pumas UNAM | - | Atlas Guadalajara | 3:2 (2:2) | |
| 12.05.2022 | 21:45 | Club Tijuana | - | Santos Laguna | 1:1 (0:0) | |
| 14.05.2022 | 16:00 | Atlas Guadalajara | - | Pumas UNAM | 4:0 (0:0) | |
| 15.05.2022 | 17:00 | Santos Laguna | - | Club Tijuana | 4:1 (1:1) | |
| Final | ||||||
| 19.05.2022 | 02:00 | Santos Laguna | - | Atlas Guadalajara | 0:1 (0:1) | |
| 21.05.2022 | 16:00 | Atlas Guadalajara | - | Santos Laguna | 3:1 (1:0) | |
