16.04.2021 17:00 Great Olympics - Asante Kotoko 0:0 (0:0)
17.04.2021 17:00 Elmina Sharks - WAFA 1:0 (0:0)
17:30 King Faisal - Ashanti Gold 0:0 (0:0)
18.04.2021 17:00 Bechem United - Aduana Stars 4:0 (3:0)
17:00 Berekum Chelsea - Ebusua Dwarfs 2:1 (0:1)
17:00 Eleven Wonders - Liberty Professionals 0:1 (0:0)
17:00 Medeama SC - Legon Cities 2:1 (1:0)
20:00 Hearts of Oak - Inter Allies 1:0 (1:0)
19.04.2021 12:00 Dreams FC - Karela FC 1:0 (0:0)
# Equipo P V E D Goles DG Pun.
1 Asante Kotoko, Ghana Asante Kotoko 20 9 8 3 20:8 12 35
2 Great Olympics, Ghana Great Olympics 20 10 4 6 21:15 6 34
3 Hearts of Oak, Ghana Hearts of Oak 20 9 6 5 28:15 13 33
4 Medeama SC, Ghana Medeama SC 20 9 6 5 24:18 6 33
5 Karela FC, Ghana Karela FC 20 9 5 6 26:21 5 32
6 Dreams FC, Ghana Dreams FC 20 8 6 6 28:20 8 30
7 Bechem United, Ghana Bechem United 20 8 6 6 25:26 -1 30
8 Ashanti Gold, Ghana Ashanti Gold 20 6 9 5 29:25 4 27
9 Berekum Chelsea, Ghana Berekum Chelsea 20 7 6 7 21:23 -2 27
10 Aduana Stars, Ghana Aduana Stars 20 7 6 7 22:28 -6 27
11 WAFA, Ghana WAFA 20 7 5 8 24:24 0 26
12 Elmina Sharks, Ghana Elmina Sharks 20 6 8 6 20:26 -6 26
13 Ebusua Dwarfs, Ghana Ebusua Dwarfs 20 6 6 8 22:25 -3 24
14 Legon Cities, Ghana Legon Cities 20 5 7 8 19:20 -1 22
15 Eleven Wonders, Ghana Eleven Wonders 20 5 7 8 15:21 -6 22
16 Liberty Professionals, Ghana Liberty Professionals 20 5 6 9 16:25 -9 21
17 King Faisal, Ghana King Faisal 20 4 7 9 19:30 -11 19
18 Inter Allies, Ghana Inter Allies 20 4 4 12 12:21 -9 16
  Champions League
  Descenso