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| 18.09.2010 | 16:15 | Iraklis Saloniki | - | AE Lárissa | 1:0 (1:0) | |
| 16:15 | Ergotelis | - | Skoda Xanthi | 1:0 (0:0) | ||
| 18:30 | AO Kavala | - | Panathinaikos | 2:2 (2:1) | ||
| 19.09.2010 | 15:00 | AO Kerkyra | - | Atromitos | 3:1 (1:0) | |
| 17:15 | Panionios GSS | - | Aris Saloniki | 1:0 (0:0) | ||
| 17:15 | Panserraikos | - | Olympiacos | 0:1 (0:1) | ||
| 17:15 | PAOK Saloniki | - | Olympiacos Volou | 1:1 (1:1) | ||
| 19:30 | AEK Athen | - | Asteras Tripolis | 2:2 (0:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Iraklis Saloniki | 3 | 2 | 1 | 0 | 4:2 | 2 | 7 |
| 2 |
|
Olympiacos | 3 | 2 | 0 | 1 | 4:2 | 2 | 6 |
| 3 |
|
AO Kerkyra | 3 | 2 | 0 | 1 | 5:4 | 1 | 6 |
| 4 |
|
Ergotelis | 3 | 2 | 0 | 1 | 2:1 | 1 | 6 |
| 5 |
|
Panathinaikos | 3 | 1 | 2 | 0 | 4:3 | 1 | 5 |
|
PAOK Saloniki | 3 | 1 | 2 | 0 | 4:3 | 1 | 5 | |
| 7 |
|
Asteras Tripolis | 3 | 1 | 2 | 0 | 3:2 | 1 | 5 |
| 8 |
|
AEK Athen | 3 | 1 | 1 | 1 | 5:4 | 1 | 4 |
| 9 |
|
Olympiacos Volou | 3 | 1 | 1 | 1 | 2:2 | 0 | 4 |
| 10 |
|
AE Lárissa | 3 | 1 | 1 | 1 | 1:1 | 0 | 4 |
| 11 |
|
Panionios GSS | 3 | 1 | 1 | 1 | 2:2 | 0 | 4 |
| 12 |
|
Aris Saloniki | 3 | 1 | 0 | 2 | 1:2 | -1 | 3 |
| 13 |
|
AO Kavala | 3 | 0 | 2 | 1 | 2:3 | -1 | 2 |
|
Skoda Xanthi | 3 | 0 | 2 | 1 | 2:3 | -1 | 2 | |
| 15 |
|
Atromitos | 3 | 0 | 1 | 2 | 2:5 | -3 | 1 |
| 16 |
|
Panserraikos | 3 | 0 | 0 | 3 | 2:6 | -4 | 0 |
| Champions League | |
| Playoff | |
| Descenso |
