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| I | Deportivo Toluca | - | CF América | 2:1 (2:0) | ||
| V | CF América | - | Deportivo Toluca | 1:1 (1:1) | ||
| I: 20.10.2022 04:06 | V: 23.10.2022 03:06 | Campeones: Deportivo Toluca | ||||
| I | CF Pachuca | - | CF Monterrey | 5:2 (2:2) | ||
| V | CF Monterrey | - | CF Pachuca | 0:1 (0:0) | ||
| I: 21.10.2022 04:06 | V: 24.10.2022 03:06 | Campeones: CF Pachuca | ||||
