 |
 |
|
|
| 04.03.2022 | 23:00 | General Caballero DJLM | - | Club Nacional | 1:2 (0:1) | |
| 05.03.2022 | 22:00 | Resistencia SC | - | Guaireña FC | 2:2 (1:0) | |
| 06.03.2022 | 00:15 | Cerro Porteño | - | Sol de América | 4:0 (2:0) | |
| 22:00 | Libertad | - | Sportivo Ameliano | 2:0 (1:0) | ||
| 07.03.2022 | 00:15 | Club Olimpia | - | Tacuary | 2:0 (1:0) | |
| 23:00 | 12 de Octubre de Itauguá | - | Guaraní | 1:3 (0:2) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Cerro Porteño | 5 | 5 | 0 | 0 | 14:4 | 10 | 15 |
| 2 |
|
Libertad | 5 | 4 | 1 | 0 | 12:3 | 9 | 13 |
| 3 |
|
Resistencia SC | 5 | 3 | 2 | 0 | 13:7 | 6 | 11 |
| 4 |
|
Club Olimpia | 5 | 3 | 2 | 0 | 10:5 | 5 | 11 |
| 5 |
|
Sol de América | 5 | 2 | 1 | 2 | 2:5 | -3 | 7 |
| 6 |
|
Guaraní | 5 | 1 | 2 | 2 | 6:7 | -1 | 5 |
| 7 |
|
Club Nacional | 5 | 1 | 2 | 2 | 7:9 | -2 | 5 |
| 8 |
|
12 de Octubre de Itauguá | 5 | 1 | 2 | 2 | 7:13 | -6 | 5 |
| 9 |
|
General Caballero DJLM | 5 | 1 | 1 | 3 | 5:6 | -1 | 4 |
| 10 |
|
Sportivo Ameliano | 5 | 1 | 0 | 4 | 5:11 | -6 | 3 |
| 11 |
|
Guaireña FC | 5 | 0 | 2 | 3 | 3:8 | -5 | 2 |
| 12 |
|
Tacuary | 5 | 0 | 1 | 4 | 1:7 | -6 | 1 |
| Copa Libertadores |
