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| 16.10.2021 | 10:00 | CSKA Moscú | - | Kuban Krasnodar | 1:2 (1:2) | |
| 10:00 | FK Strogino Moskva | - | Spartak Moskva | 2:0 (0:0) | ||
| 10:00 | Chertanovo Football Academy | - | FK Saturn | 5:2 (1:1) | ||
| 10:00 | FK Rostov | - | FK Krasnodar | 0:4 (0:3) | ||
| 10:00 | Rubin Kazan | - | FShM Moskva | 1:2 (0:1) | ||
| 11:00 | SShOR Zenit | - | Zenit | 1:1 (0:0) | ||
| 17:00 | Lokomotiv Moskva | - | Dinamo Moskva | 4:1 (3:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Chertanovo Football Academy | 11 | 9 | 1 | 1 | 26:10 | 16 | 28 |
| 2 |
|
Spartak Moskva | 11 | 8 | 1 | 2 | 30:8 | 22 | 25 |
| 3 |
|
FK Krasnodar | 11 | 8 | 1 | 2 | 29:10 | 19 | 25 |
| 4 |
|
FK Rostov | 11 | 7 | 1 | 3 | 21:13 | 8 | 22 |
| 5 |
|
Zenit | 11 | 6 | 2 | 3 | 25:18 | 7 | 20 |
| 6 |
|
SShOR Zenit | 11 | 5 | 3 | 3 | 21:18 | 3 | 18 |
| 7 |
|
Lokomotiv Moskva | 11 | 5 | 0 | 6 | 20:21 | -1 | 15 |
| 8 |
|
FK Strogino Moskva | 11 | 5 | 0 | 6 | 16:17 | -1 | 15 |
| 9 |
|
FK Saturn | 11 | 4 | 2 | 5 | 21:31 | -10 | 14 |
| 10 |
|
CSKA Moscú | 11 | 3 | 2 | 6 | 17:23 | -6 | 11 |
| 11 |
|
Kuban Krasnodar | 11 | 2 | 3 | 6 | 9:25 | -16 | 9 |
| 12 |
|
Dinamo Moskva | 11 | 2 | 1 | 8 | 15:26 | -11 | 7 |
| 13 |
|
FShM Moskva | 11 | 1 | 3 | 7 | 12:30 | -18 | 6 |
| 14 |
|
Rubin Kazan | 11 | 1 | 2 | 8 | 10:22 | -12 | 5 |
