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| 13.04.2022 | 13:00 | Kuban Krasnodar | - | Zenit | 0:3 (0:1) | |
| 15:00 | FShM Moskva | - | FK Krasnodar | 2:3 (2:3) | ||
| 15:00 | FK Saturn | - | Rubin Kazan | 1:1 (0:0) | ||
| 15:00 | Chertanovo Football Academy | - | CSKA Moscú | 5:4 (3:1) | ||
| 15:00 | FK Strogino Moskva | - | Lokomotiv Moskva | 5:0 (2:0) | ||
| 15:30 | FK Rostov | - | Dinamo Moskva | 2:0 (1:0) | ||
| 16:00 | SShOR Zenit | - | Spartak Moskva | 0:2 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FK Krasnodar | 14 | 10 | 2 | 2 | 34:13 | 21 | 32 |
| 2 |
|
Spartak Moskva | 14 | 10 | 1 | 3 | 36:10 | 26 | 31 |
| 3 |
|
Chertanovo Football Academy | 14 | 10 | 1 | 3 | 33:21 | 12 | 31 |
| 4 |
|
FK Rostov | 14 | 10 | 1 | 3 | 25:13 | 12 | 31 |
| 5 |
|
Zenit | 14 | 9 | 2 | 3 | 37:21 | 16 | 29 |
| 6 |
|
FK Strogino Moskva | 14 | 8 | 0 | 6 | 27:19 | 8 | 24 |
| 7 |
|
Lokomotiv Moskva | 14 | 6 | 1 | 7 | 25:28 | -3 | 19 |
| 8 |
|
SShOR Zenit | 14 | 5 | 3 | 6 | 22:24 | -2 | 18 |
| 9 |
|
FK Saturn | 14 | 5 | 3 | 6 | 24:33 | -9 | 18 |
| 10 |
|
Kuban Krasnodar | 14 | 3 | 4 | 7 | 13:30 | -17 | 13 |
| 11 |
|
CSKA Moscú | 14 | 3 | 2 | 9 | 22:34 | -12 | 11 |
| 12 |
|
Dinamo Moskva | 14 | 3 | 1 | 10 | 19:32 | -13 | 10 |
| 13 |
|
Rubin Kazan | 14 | 1 | 4 | 9 | 13:28 | -15 | 7 |
| 14 |
|
FShM Moskva | 14 | 1 | 3 | 10 | 15:39 | -24 | 6 |
