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| 06.03.2021 | 13:00 | FK Mariupol | - | Vorskla Poltava | 0:1 (0:1) | |
| 16:00 | Olimpik Donetsk | - | Shakhtar Donetsk | 0:1 (0:1) | ||
| 07.03.2021 | 13:00 | Dinamo Kiev | - | FC Mynai | 3:0 (0:0) | |
| 16:00 | Zorya Lugansk | - | FK Lviv | 4:0 (4:0) | ||
| 18:30 | Inhulets Petrove | - | Kolos Kovalivka | 0:0 (0:0) | ||
| 08.03.2021 | 13:00 | SK Dnipro-1 | - | FK Oleksandriya | 0:0 (0:0) | |
| 13:00 | Rukh Lviv | - | Desna Chernigov | 0:4 (0:2) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Dinamo Kiev | 17 | 12 | 4 | 1 | 36:13 | 23 | 40 |
| 2 |
|
Shakhtar Donetsk | 17 | 10 | 6 | 1 | 36:12 | 24 | 36 |
| 3 |
|
Zorya Lugansk | 17 | 9 | 5 | 3 | 32:13 | 19 | 32 |
| 4 |
|
Desna Chernigov | 17 | 8 | 6 | 3 | 27:14 | 13 | 30 |
| 5 |
|
Vorskla Poltava | 17 | 7 | 7 | 3 | 24:14 | 10 | 28 |
| 6 |
|
Kolos Kovalivka | 17 | 5 | 8 | 4 | 21:18 | 3 | 23 |
| 7 |
|
FK Oleksandriya | 17 | 6 | 5 | 6 | 24:21 | 3 | 23 |
| 8 |
|
Olimpik Donetsk | 17 | 6 | 2 | 9 | 24:29 | -5 | 20 |
| 9 |
|
FK Mariupol | 17 | 4 | 5 | 8 | 16:24 | -8 | 17 |
| 10 |
|
SK Dnipro-1 | 17 | 4 | 4 | 9 | 22:30 | -8 | 16 |
| 11 |
|
FK Lviv | 17 | 4 | 3 | 10 | 12:37 | -25 | 15 |
| 12 |
|
Inhulets Petrove | 17 | 1 | 10 | 6 | 15:27 | -12 | 13 |
| 13 |
|
Rukh Lviv | 17 | 2 | 7 | 8 | 15:31 | -16 | 13 |
| 14 |
|
FC Mynai | 17 | 3 | 4 | 10 | 12:33 | -21 | 13 |
| Champions League | |
| CL Ronda previa | |
| ECL Ronda previa | |
| Descenso |
