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| 09.11.2012 | 20:30 | Holyhead Hotspur | - | Pwllheli FC | 5:2 | |
| 10.11.2012 | 14:00 | Llanrhaeadr-ym-Mochnant | - | Llanrug United | 2:3 | |
| 14:00 | Brymbo FC | - | Cefn Druids | 1:3 | ||
| 14:00 | Corwen FC | - | CPD Gwalchmai | 1:2 pró. | ||
| 14:00 | Waterloo Rovers | - | Rhyl FC | 0:5 | ||
| 14:00 | Montgomery Town | - | Llandudno Junction FC | 1:3 | ||
| 14:00 | Newbridge-on-Wye FC | - | Monmouth Town | 1:5 | ||
| 14:00 | West End FC | - | Rhayader Town | 2:0 | ||
| 14:00 | Chepstow Town FC | - | Grange Quins | 4:1 | ||
| 14:30 | Holywell Town | - | Llandudno FC | 3:5 pró. | ||
| 14:30 | Llanidloes Town FC | - | Caersws FC | 3:2 | ||
| 14:30 | Conwy Borough FC | - | Buckley Town | 4:3 pn. | ||
| 14:30 | Flint Town United | - | Greenfield FC | 3:0 | ||
| 14:30 | Penrhyncoch FC | - | Barry Town FC | 1:2 | ||
| 14:30 | Aberdare Town FC | - | Tata Steel | 2:1 | ||
| 14:30 | Ely Rangers | - | Aberbargoed Buds | 6:1 | ||
| 17.11.2012 | 15:00 | Caerau FC | - | Goytre AFC | 1:3 | |
| 15:00 | Pontardawe Town | - | Ton Pentre FC | 2:0 | ||
| 15:30 | Goytre United | - | Caerau Ely AFC | 2:4 | ||
| 15:30 | Cambrian & Clydach | - | Haverfordwest County | 0:1 |
