| 7. Jornada | 21.02.2016 | Pumas UNAM | - | Santos Laguna | 1:1 | ||||
| 8. Jornada | 28.02.2016 | Santos Laguna | - | Puebla FC | 1:1 | ||||
| 9. Jornada | 06.03.2016 | Atlas Guadalajara | - | Santos Laguna | 1:2 | ||||
| 10. Jornada | 12.03.2016 | Santos Laguna | - | CF Pachuca | 3:2 | ||||
| 11. Jornada | 20.03.2016 | Dorados de Sinaloa | - | Santos Laguna | 3:1 |  |
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| 15. Jornada | 24.04.2016 | Santos Laguna | - | UANL Tigres | 2:1 |
México
