| 1. Jornada | 04.04.2021 | Deportes Temuco | - | San Luis | 2:2 | ||||
| 2. Jornada | 19.04.2021 | San Luis | - | Rangers | 0:1 | ||||
| 3. Jornada | 26.04.2021 | Puerto Montt | - | San Luis | 2:1 | ||||
| 8. Jornada | 30.05.2021 | Cobreloa | - | San Luis | 1:0 | ||||
| 9. Jornada | 07.06.2021 | San Luis | - | San Marcos | 0:1 | ||||
| 12. Jornada | 23.07.2021 | San Luis | - | Universidad de Concepción | 1:0 |  |
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| 13. Jornada | 01.08.2021 | Coquimbo Unido | - | San Luis | 0:1 | ||||
| 15. Jornada | 17.08.2021 | Barnechea | - | San Luis | 0:0 | ||||
| 16. Jornada | 23.08.2021 | San Luis | - | Deportes Temuco | 1:1 | ||||
| 18. Jornada | 01.09.2021 | San Luis | - | Puerto Montt | 0:1 |
Argentina