| 1. Jornada | 23.07.2021 | FK Rostov | - | Dinamo Moskva | 0:2 | ||||
| 2. Jornada | 01.08.2021 | FK Rostov | - | Zenit | 2:4 | ||||
| 7. Jornada | 13.09.2021 | FK Rostov | - | FK Krasnodar | 1:1 |  |
|||
| 8. Jornada | 18.09.2021 | Krylia Sovetov | - | FK Rostov | 4:2 | ||||
| 17. Jornada | 03.12.2021 | Zenit | - | FK Rostov | 2:2 | ||||
| 18. Jornada | 11.12.2021 | FK Rostov | - | FK Ural | 1:4 | |
|||
| 20. Jornada | 07.03.2022 | FK Rostov | - | FK Sochi | 0:1 | ||||
| 21. Jornada | 14.03.2022 | Rubin Kazan | - | FK Rostov | 1:2 | ||||
| 22. Jornada | 20.03.2022 | Dinamo Moskva | - | FK Rostov | 1:1 | ||||
| 23. Jornada | 02.04.2022 | FK Rostov | - | FK Nizhny Novgorod | 1:2 | ||||
| 19. Jornada | 06.04.2022 | FK Rostov | - | Krylia Sovetov | 1:0 | |
|||
| 24. Jornada | 10.04.2022 | FK Rostov | - | Lokomotiv Moskva | 4:1 | ||||
| 25. Jornada | 17.04.2022 | Arsenal Tula | - | FK Rostov | 1:2 | |
|||
| 28. Jornada | 08.05.2022 | FK Ufa | - | FK Rostov | 0:0 | ||||
| 29. Jornada | 14.05.2022 | FK Rostov | - | FK Khimki | 2:1 | |
|||
| 30. Jornada | 21.05.2022 | CSKA Moscú | - | FK Rostov | 4:0 |
Rusia