| 2. Jornada | 12.03.2022 | Omonia Nikosia | - | Doxa Katokopias | 2:2 |  |
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| 3. Jornada | 19.03.2022 | AEL Limassol | - | Omonia Nikosia | 1:1 |  |
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| 5. Jornada | 08.04.2022 | Olympiacos Nikosia | - | Omonia Nikosia | 3:0 | ||||
| 6. Jornada | 17.04.2022 | Omonia Nikosia | - | Ethnikos Achna | 1:0 | |
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| 1. Jornada | 20.04.2022 | Ethnikos Achna | - | Omonia Nikosia | 0:0 | ||||
| 7. Jornada | 01.05.2022 | Doxa Katokopias | - | Omonia Nikosia | 0:2 | ||||
| 8. Jornada | 07.05.2022 | Omonia Nikosia | - | AEL Limassol | 3:2 | ||||
| 9. Jornada | 14.05.2022 | PAEEK | - | Omonia Nikosia | 2:5 | ||||
| 10. Jornada | 20.05.2022 | Omonia Nikosia | - | Olympiacos Nikosia | 1:1 |
Chipre