| 1. Jornada | 08.01.2022 | Deportivo Guadalajara [Sub 16] | - | Atlético San Luis [Sub 16] | 1:1 | ||||
| 4. Jornada | 29.01.2022 | Santos Laguna [Sub 16] | - | Deportivo Guadalajara [Sub 16] | 0:1 | ||||
| 7. Jornada | 19.02.2022 | Deportivo Guadalajara [Sub 16] | - | Mazatlán FC [Sub 16] | 7:1 | ||||
| 9. Jornada | 05.03.2022 | Deportivo Guadalajara [Sub 16] | - | Atlas Guadalajara [Sub 16] | 2:3 | ||||
| 14. Jornada | 09.04.2022 | Mazatlán FC [Sub 16] | - | Deportivo Guadalajara [Sub 16] | 1:2 | ||||
| 17. Jornada | 30.04.2022 | Deportivo Guadalajara [Sub 16] | - | Santos Laguna [Sub 16] | 3:0 |
México