| 23. Jornada | 06.02.2022 | BB Erzurumspor | - | Manisa FK | 1:0 | ||||
| 28. Jornada | 06.03.2022 | Adanaspor | - | Manisa FK | 2:0 | ||||
| 29. Jornada | 20.03.2022 | Manisa FK | - | MKE Ankaragücü | 1:1 |  |
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| 30. Jornada | 02.04.2022 | Boluspor | - | Manisa FK | 1:2 | ||||
| 31. Jornada | 10.04.2022 | Manisa FK | - | Samsunspor | 2:0 | ||||
| 32. Jornada | 16.04.2022 | Altınordu FK | - | Manisa FK | 1:0 | ||||
| 33. Jornada | 20.04.2022 | Manisa FK | - | Balıkesirspor | 3:0 | ||||
| 34. Jornada | 24.04.2022 | Kocaelispor | - | Manisa FK | 2:1 | ||||
| 35. Jornada | 01.05.2022 | Manisa FK | - | Bursaspor | 1:3 | |
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| 36. Jornada | 08.05.2022 | Keçiörengücü | - | Manisa FK | 2:1 | ||||
| 37. Jornada | 14.05.2022 | Manisa FK | - | Tuzlaspor | 4:1 |
Turquía