| 1. Jornada | 04.04.2021 | Cobreloa | - | Barnechea | 1:2 | ||||
| 2. Jornada | 18.04.2021 | San Marcos | - | Cobreloa | 0:0 |  |
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| 3. Jornada | 26.04.2021 | Cobreloa | - | Universidad de Concepción | 2:4 |  |
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| 4. Jornada | 04.05.2021 | Cobreloa | - | Coquimbo Unido | 1:1 | |
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| 5. Jornada | 10.05.2021 | Unión San Felipe | - | Cobreloa | 0:0 | ||||
| 6. Jornada | 18.05.2021 | Cobreloa | - | Santiago Morning | 2:2 | |
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| 8. Jornada | 30.05.2021 | Cobreloa | - | San Luis | 1:0 | ||||
| 9. Jornada | 07.06.2021 | CD Magallanes | - | Cobreloa | 2:2 | |
Argentina