| 5. Jornada | 04.02.2021 | Atlético San Luis [Sub 20] | - | Club Tijuana [Sub 20] | 1:2 | ||||
| 6. Jornada | 12.02.2021 | Mazatlán FC [Sub 20] | - | Atlético San Luis [Sub 20] | 1:0 | ||||
| 7. Jornada | 18.02.2021 | Atlético San Luis [Sub 20] | - | Santos Laguna [Sub 20] | 0:4 | ||||
| 8. Jornada | 25.02.2021 | Atlético San Luis [Sub 20] | - | UANL Tigres [Sub 20] | 2:1 |  |
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| 9. Jornada | 02.03.2021 | Atlas Guadalajara [Sub 20] | - | Atlético San Luis [Sub 20] | 2:0 | ||||
| 10. Jornada | 05.03.2021 | Atlético San Luis [Sub 20] | - | Deportivo Toluca [Sub 20] | 1:2 | ||||
| 11. Jornada | 14.03.2021 | Gallos Blancos [Sub 20] | - | Atlético San Luis [Sub 20] | 0:1 | ||||
| 12. Jornada | 20.03.2021 | Atlético San Luis [Sub 20] | - | Pumas UNAM [Sub 20] | 2:1 | ||||
| 4. Jornada | 26.03.2021 | Club León [Sub 20] | - | Atlético San Luis [Sub 20] | 4:2 | ||||
| 13. Jornada | 03.04.2021 | CF Monterrey [Sub 20] | - | Atlético San Luis [Sub 20] | 4:1 |  |
México
Estados Unidos