| 1. Jornada | 12.02.2022 | Temperley | - | San Martín de Tucumán | 1:2 | ||||
| 2. Jornada | 19.02.2022 | Defensores de Belgrano | - | Temperley | 0:2 |  |
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| 3. Jornada | 28.02.2022 | Temperley | - | Brown de Adrogué | 0:1 | ||||
| 5. Jornada | 12.03.2022 | Temperley | - | Guillermo Brown | 0:1 | ||||
| 6. Jornada | 18.03.2022 | Atlético Rafaela | - | Temperley | 1:0 | ||||
| 7. Jornada | 24.03.2022 | Temperley | - | Ramón Santamarina | 3:1 | |
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| 8. Jornada | 28.03.2022 | Estudiantes de Caseros | - | Temperley | 0:0 | ||||
| 9. Jornada | 04.04.2022 | Temperley | - | Atlanta | 0:2 | ||||
| 10. Jornada | 09.04.2022 | San Martín de San Juan | - | Temperley | 4:1 | ||||
| 11. Jornada | 16.04.2022 | Temperley | - | Chaco For Ever | 0:0 | ||||
| 12. Jornada | 23.04.2022 | San Telmo | - | Temperley | 3:1 | ||||
| 16. Jornada | 23.05.2022 | Deportivo Riestra | - | Temperley | 1:2 |
Argentina