| 1. Jornada | 09.01.2022 | Deportivo Guadalajara [Sub 18] | - | Mazatlán FC [Sub 18] | 4:1 | ||||
| 3. Jornada | 21.01.2022 | Mazatlán FC [Sub 18] | - | Deportivo Toluca [Sub 18] | 0:0 | ||||
| 5. Jornada | 11.02.2022 | Mazatlán FC [Sub 18] | - | Club Tijuana [Sub 18] | 0:2 | ||||
| 8. Jornada | 01.03.2022 | Mazatlán FC [Sub 18] | - | Club Necaxa [Sub 18] | 2:0 | ||||
| 10. Jornada | 11.03.2022 | CF Monterrey [Sub 18] | - | Mazatlán FC [Sub 18] | 2:2 | ||||
| 11. Jornada | 18.03.2022 | Mazatlán FC [Sub 18] | - | Club León [Sub 18] | 1:1 |  |
México