| 4. Jornada | 02.08.2021 | Talleres de Córdoba II | - | Boca Juniors II | 1:1 | ||||
| 5. Jornada | 06.08.2021 | Boca Juniors II | - | Argentinos Juniors II | 0:1 | ||||
| 11. Jornada | 09.09.2021 | Boca Juniors II | - | Defensa y Justicia II | 3:2 |  |
|||
| 13. Jornada | 24.09.2021 | Boca Juniors II | - | Colón de Santa Fe II | 3:1 | ||||
| 14. Jornada | 01.10.2021 | River Plate II | - | Boca Juniors II | 0:3 | |
|||
| 16. Jornada | 13.10.2021 | Huracán II | - | Boca Juniors II | 1:2 | ||||
| 17. Jornada | 19.10.2021 | Boca Juniors II | - | Godoy Cruz II | 6:0 | |
|||
| 18. Jornada | 25.10.2021 | Vélez Sarsfield II | - | Boca Juniors II | 1:2 | |
|||
| 21. Jornada | 18.11.2021 | Boca Juniors II | - | Sarmiento de Junín II | 4:4 | |
|||
| 22. Jornada | 24.11.2021 | Independiente II | - | Boca Juniors II | 0:0 |
Argentina