| 1. Jornada | 13.03.2021 | San Telmo | - | Barracas Central | 1:1 | ||||
| 2. Jornada | 22.03.2021 | Independiente Rivadavia | - | San Telmo | 4:3 |  |
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| 3. Jornada | 28.03.2021 | San Telmo | - | Atlético Rafaela | 0:0 | ||||
| 4. Jornada | 04.04.2021 | Guillermo Brown | - | San Telmo | 1:2 | ||||
| 5. Jornada | 11.04.2021 | San Telmo | - | Brown de Adrogué | 2:1 |  |
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| 7. Jornada | 25.04.2021 | San Telmo | - | Villa Dálmine | 1:0 | ||||
| 8. Jornada | 02.05.2021 | San Telmo | - | All Boys | 1:1 | ||||
| 9. Jornada | 10.05.2021 | Defensores de Belgrano | - | San Telmo | 0:0 | ||||
| 10. Jornada | 16.05.2021 | San Telmo | - | Ramón Santamarina | 2:2 |
Argentina