| 6. Jornada | 02.07.2022 | River Plate II | - | Huracán II | 1:0 | ||||
| 7. Jornada | 09.07.2022 | Godoy Cruz II | - | River Plate II | 0:1 | ||||
| 8. Jornada | 16.07.2022 | River Plate II | - | Vélez Sarsfield II | 0:2 | ||||
| 9. Jornada | 20.07.2022 | Gimnasia de La Plata II | - | River Plate II | 1:3 |  |
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| 10. Jornada | 25.07.2022 | River Plate II | - | Aldosivi II | 2:0 | ||||
| 11. Jornada | 30.07.2022 | Sarmiento de Junín II | - | River Plate II | 0:1 | ||||
| 18. Jornada | 10.09.2022 | River Plate II | - | Boca Juniors II | 1:2 | ||||
| 19. Jornada | 15.09.2022 | Banfield II | - | River Plate II | 0:1 | ||||
| 20. Jornada | 19.09.2022 | River Plate II | - | San Lorenzo II | 1:0 | ||||
| 21. Jornada | 24.09.2022 | Talleres de Córdoba II | - | River Plate II | 5:0 | ||||
| 22. Jornada | 29.09.2022 | River Plate II | - | Argentinos Juniors II | 1:0 | |
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| 23. Jornada | 04.10.2022 | Estudiantes II | - | River Plate II | 2:0 | ||||
| 24. Jornada | 08.10.2022 | River Plate II | - | Patronato de Paraná II | 2:0 | ||||
| 25. Jornada | 12.10.2022 | Platense II | - | River Plate II | 0:1 | ||||
| 26. Jornada | 16.10.2022 | Rosario Central II | - | River Plate II | 3:3 | ||||
| 27. Jornada | 20.10.2022 | River Plate II | - | Racing Club II | 1:2 |
Colombia