| 2. Jornada | 15.02.2022 | Atlético Tucumán II | - | Platense II | 3:1 |  |
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| 3. Jornada | 19.02.2022 | Unión de Santa Fe II | - | Atlético Tucumán II | 1:0 | ||||
| 4. Jornada | 25.02.2022 | Atlético Tucumán II | - | Patronato de Paraná II | 4:1 | |
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| 7. Jornada | 21.03.2022 | Atlético Tucumán II | - | Central Córdoba SdE II | 2:2 | ||||
| 8. Jornada | 04.04.2022 | San Lorenzo II | - | Atlético Tucumán II | 1:1 | |
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| 12. Jornada | 25.04.2022 | River Plate II | - | Atlético Tucumán II | 4:0 | ||||
| 13. Jornada | 30.04.2022 | Atlético Tucumán II | - | Talleres de Córdoba II | 0:2 |
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