| 1. Jornada | 12.02.2021 | Unión de Santa Fe II | - | Atlético Tucumán II | 2:1 | ||||
| 2. Jornada | 19.02.2021 | Atlético Tucumán II | - | Central Córdoba SdE II | 2:0 | ||||
| 3. Jornada | 26.02.2021 | Atlético Tucumán II | - | Huracán II | 1:2 | ||||
| 4. Jornada | 05.03.2021 | Lanús II | - | Atlético Tucumán II | 2:3 | ||||
| 5. Jornada | 12.03.2021 | Atlético Tucumán II | - | Patronato de Paraná II | 2:2 | ||||
| 6. Jornada | 19.03.2021 | Gimnasia de La Plata II | - | Atlético Tucumán II | 0:0 | ||||
| 7. Jornada | 26.03.2021 | Atlético Tucumán II | - | Newell's Old Boys II | 0:1 | ||||
| 8. Jornada | 02.04.2021 | Sarmiento de Junín II | - | Atlético Tucumán II | 4:2 | ||||
| 9. Jornada | 09.04.2021 | Atlético Tucumán II | - | Vélez Sarsfield II | 3:1 |  |
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| 10. Jornada | 16.04.2021 | Boca Juniors II | - | Atlético Tucumán II | 3:1 | |
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| 11. Jornada | 23.04.2021 | Atlético Tucumán II | - | Talleres de Córdoba II | 2:2 | |
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| 13. Jornada | 07.05.2021 | Atlético Tucumán II | - | Defensa y Justicia II | 3:4 |
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