| 1. Jornada | 25.06.2022 | Santos Laguna [Sub 16] | - | Deportivo Guadalajara [Sub 16] | 1:0 | ||||
| 2. Jornada | 03.07.2022 | Deportivo Guadalajara [Sub 16] | - | Atlas Guadalajara [Sub 16] | 2:1 |  |
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| 3. Jornada | 09.07.2022 | UANL Tigres [Sub 16] | - | Deportivo Guadalajara [Sub 16] | 1:3 | ||||
| 4. Jornada | 16.07.2022 | Deportivo Guadalajara [Sub 16] | - | Club León [Sub 16] | 4:2 | |
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| 6. Jornada | 30.07.2022 | Club Tijuana [Sub 16] | - | Deportivo Guadalajara [Sub 16] | 2:2 | |
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| 7. Jornada | 06.08.2022 | Deportivo Guadalajara [Sub 16] | - | CF Monterrey [Sub 16] | 3:2 | ||||
| 8. Jornada | 13.08.2022 | Atlético San Luis [Sub 16] | - | Deportivo Guadalajara [Sub 16] | 0:0 | ||||
| 10. Jornada | 27.08.2022 | Deportivo Guadalajara [Sub 16] | - | Santos Laguna [Sub 16] | 1:0 | |
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| 11. Jornada | 03.09.2022 | Mazatlán FC [Sub 16] | - | Deportivo Guadalajara [Sub 16] | 1:2 | |
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México