| 1. Jornada | 16.07.2021 | Arsenal de Sarandí II | - | San Lorenzo II | 0:1 | ||||
| 10. Jornada | 05.09.2021 | Platense II | - | San Lorenzo II | 1:1 | ||||
| 11. Jornada | 10.09.2021 | San Lorenzo II | - | Racing Club II | 0:0 | ||||
| 14. Jornada | 01.10.2021 | Atlético Tucumán II | - | San Lorenzo II | 1:1 | ||||
| 15. Jornada | 11.10.2021 | San Lorenzo II | - | Colón de Santa Fe II | 1:1 | ||||
| 18. Jornada | 22.10.2021 | Huracán II | - | San Lorenzo II | 0:1 | ||||
| 24. Jornada | 06.12.2021 | Independiente II | - | San Lorenzo II | 1:0 | ||||
| 25. Jornada | 10.12.2021 | San Lorenzo II | - | Newell's Old Boys II | 2:1 |  |
Argentina
Gales