| 1. Jornada | 08.08.2021 | FK AP Brera Strumica | - | FC Struga | 1:1 | ||||
| 2. Jornada | 15.08.2021 | FK AP Brera Strumica | - | FK Rabotnički | 2:0 | ||||
| 3. Jornada | 18.08.2021 | GFK Tikvesh | - | FK AP Brera Strumica | 0:2 | ||||
| 4. Jornada | 22.08.2021 | FK AP Brera Strumica | - | FK Renova | 2:1 | ||||
| 5. Jornada | 28.08.2021 | FK Bregalnica Štip | - | FK AP Brera Strumica | 3:2 | ||||
| 6. Jornada | 12.09.2021 | FK AP Brera Strumica | - | Makedonija GP | 4:1 |  |
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| 7. Jornada | 19.09.2021 | FK Pelister | - | FK AP Brera Strumica | 0:0 | ||||
| 8. Jornada | 26.09.2021 | FK AP Brera Strumica | - | KF Shkupi | 1:3 | |
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| 9. Jornada | 02.10.2021 | FK Skopje | - | FK AP Brera Strumica | 0:0 | ||||
| 17. Jornada | 08.12.2021 | Makedonija GP | - | FK AP Brera Strumica | 4:1 | |
Brasil