| 3. Jornada | 20.02.2022 | General Caballero DJLM | - | Tacuary | 2:0 | ||||
| 8. Jornada | 04.04.2022 | Guaraní | - | Tacuary | 1:2 | ||||
| 16. Jornada | 16.05.2022 | Tacuary | - | Club Olimpia | 1:4 | ||||
| 17. Jornada | 20.05.2022 | Tacuary | - | Sportivo Ameliano | 1:0 | ||||
| 19. Jornada | 20.06.2022 | Tacuary | - | Guaraní | 0:2 | ||||
| 20. Jornada | 24.06.2022 | Guaireña FC | - | Tacuary | 0:0 | ||||
| 21. Jornada | 28.06.2022 | Tacuary | - | Sol de América | 2:2 |  |
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| 22. Jornada | 02.07.2022 | Cerro Porteño | - | Tacuary | 1:0 |
Paraguay