| 1. Jornada | 04.02.2018 | Guaraní | - | Sol de América | 6:2 |  |
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| 2. Jornada | 11.02.2018 | Libertad | - | Guaraní | 2:0 | ||||
| 4. Jornada | 26.02.2018 | Club Olimpia | - | Guaraní | 5:2 | ||||
| 5. Jornada | 05.03.2018 | Guaraní | - | Independiente CG | 0:1 | ||||
| 6. Jornada | 11.03.2018 | General Díaz | - | Guaraní | 0:3 | ||||
| 9. Jornada | 24.03.2018 | Deportivo Santaní | - | Guaraní | 2:0 |  |
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| 13. Jornada | 22.04.2018 | Guaraní | - | Libertad | 0:2 | ||||
| 16. Jornada | 08.05.2018 | Independiente CG | - | Guaraní | 2:1 | ||||
| 19. Jornada | 26.05.2018 | Club Nacional | - | Guaraní | 3:0 |
Paraguay
España 
