| 1. Jornada | 11.09.2021 | Panathinaikos | - | Apollon Smyrnis | 4:0 | ||||
| 2. Jornada | 18.09.2021 | PAS Giannina | - | Panathinaikos | 1:0 | ||||
| 3. Jornada | 22.09.2021 | Aris Saloniki | - | Panathinaikos | 1:0 | ||||
| 4. Jornada | 26.09.2021 | Panathinaikos | - | Volos NFC | 5:1 | ||||
| 5. Jornada | 03.10.2021 | Olympiacos | - | Panathinaikos | 0:0 |  |
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| 10. Jornada | 22.11.2021 | Lamia | - | Panathinaikos | 1:3 |  |
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| 16. Jornada | 05.01.2022 | Panathinaikos | - | Aris Saloniki | 2:0 | ||||
| 17. Jornada | 09.01.2022 | Volos NFC | - | Panathinaikos | 3:1 | ||||
| 20. Jornada | 29.01.2022 | Panathinaikos | - | Asteras Tripolis | 0:1 | ||||
| 21. Jornada | 02.02.2022 | OFI Heraklion | - | Panathinaikos | 3:2 | ||||
| 22. Jornada | 06.02.2022 | PAOK Saloniki | - | Panathinaikos | 2:1 |
Suecia
Nicaragua