| 1. Jornada | 10.02.2022 | Patronato de Paraná II | - | Argentinos Juniors II | 0:1 | ||||
| 2. Jornada | 15.02.2022 | Argentinos Juniors II | - | Newell's Old Boys II | 1:1 |  |
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| 3. Jornada | 19.02.2022 | Racing Club II | - | Argentinos Juniors II | 0:4 | ||||
| 4. Jornada | 26.02.2022 | Argentinos Juniors II | - | San Lorenzo II | 2:0 | |
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| 11. Jornada | 21.04.2022 | Atlético Tucumán II | - | Argentinos Juniors II | 2:1 | ||||
| 12. Jornada | 25.04.2022 | Argentinos Juniors II | - | Sarmiento de Junín II | 0:0 | ||||
| 14. Jornada | 05.05.2022 | Argentinos Juniors II | - | Unión de Santa Fe II | 4:0 |
Argentina