| 1. Jornada | 14.07.2019 | Sol de América | - | Club Nacional | 2:1 |  |
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| 4. Jornada | 04.08.2019 | River Plate | - | Club Nacional | 0:1 | ||||
| 5. Jornada | 09.08.2019 | Club Nacional | - | Libertad | 1:0 | |
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| 6. Jornada | 16.08.2019 | Sportivo Luqueño | - | Club Nacional | 1:1 | |
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| 7. Jornada | 27.08.2019 | Club Nacional | - | Cerro Porteño | 1:1 | ||||
| 8. Jornada | 01.09.2019 | Deportivo Santaní | - | Club Nacional | 3:1 | |
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| 9. Jornada | 15.09.2019 | Club Nacional | - | Deportivo Capiatá | 3:0 | |
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| 12. Jornada | 29.09.2019 | Club Nacional | - | Sol de América | 0:0 | ||||
| 13. Jornada | 06.10.2019 | Club Olimpia | - | Club Nacional | 3:0 | ||||
| 14. Jornada | 19.10.2019 | Club Nacional | - | General Díaz | 0:0 | ||||
| 15. Jornada | 26.10.2019 | Club Nacional | - | River Plate | 1:1 | |
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| 16. Jornada | 02.11.2019 | Libertad | - | Club Nacional | 2:0 | |
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| 18. Jornada | 10.11.2019 | Cerro Porteño | - | Club Nacional | 5:0 | |
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| 17. Jornada | 24.11.2019 | Club Nacional | - | Sportivo Luqueño | 1:1 | ||||
| 21. Jornada | 09.12.2019 | Club Nacional | - | San Lorenzo | 4:2 | |
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| 22. Jornada | 15.12.2019 | Guaraní | - | Club Nacional | 0:5 | |
Paraguay