| 1. Jornada | 10.02.2022 | Newell's Old Boys II | - | Defensa y Justicia II | 2:0 |  |
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| 5. Jornada | 04.03.2022 | Newell's Old Boys II | - | Atlético Tucumán II | 2:3 | |
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| 6. Jornada | 10.03.2022 | Sarmiento de Junín II | - | Newell's Old Boys II | 1:2 | ||||
| 13. Jornada | 30.04.2022 | Newell's Old Boys II | - | San Lorenzo II | 0:3 | ||||
| 14. Jornada | 05.05.2022 | Gimnasia de La Plata II | - | Newell's Old Boys II | 1:3 |
Argentina