| 1. Jornada | 23.02.2025 | St. Louis City SC | - | Colorado Rapids | 0:0 | ||||
| 2. Jornada | 02.03.2025 | San Diego FC | - | St. Louis City SC | 0:0 | ||||
| 3. Jornada | 10.03.2025 | Los Angeles Galaxy | - | St. Louis City SC | 0:3 | ||||
| 13. Jornada | 15.05.2025 | St. Louis City SC | - | Sporting Kansas City | 2:2 | ||||
| 14. Jornada | 18.05.2025 | Minnesota United FC | - | St. Louis City SC | 3:0 | ||||
| 15. Jornada | 25.05.2025 | Colorado Rapids | - | St. Louis City SC | 1:0 | ||||
| 17. Jornada | 31.05.2025 | St. Louis City SC | - | San Jose Earthquakes | 2:1 | ||||
| 18. Jornada | 09.06.2025 | Portland Timbers | - | St. Louis City SC | 2:1 | ||||
| 18. Jornada | 14.06.2025 | St. Louis City SC | - | Los Angeles Galaxy | 3:3 | ||||
| 19. Jornada | 26.06.2025 | St. Louis City SC | - | Orlando City | 2:4 | ||||
| 20. Jornada | 29.06.2025 | Houston Dynamo | - | St. Louis City SC | 1:0 |
Suiza
