| 2. Jornada | 23.07.2021 | Argentinos Juniors II | - | Newell's Old Boys II | 3:1 | ||||
| 5. Jornada | 06.08.2021 | Boca Juniors II | - | Argentinos Juniors II | 0:1 | ||||
| 7. Jornada | 20.08.2021 | San Lorenzo II | - | Argentinos Juniors II | 1:3 | ||||
| 10. Jornada | 03.09.2021 | Estudiantes II | - | Argentinos Juniors II | 2:0 | ||||
| 11. Jornada | 10.09.2021 | Argentinos Juniors II | - | Patronato de Paraná II | 3:0 | ||||
| 12. Jornada | 16.09.2021 | Platense II | - | Argentinos Juniors II | 2:2 | ||||
| 13. Jornada | 27.09.2021 | Argentinos Juniors II | - | Racing Club II | 2:1 | ||||
| 14. Jornada | 01.10.2021 | Rosario Central II | - | Argentinos Juniors II | 0:2 | ||||
| 16. Jornada | 17.10.2021 | Atlético Tucumán II | - | Argentinos Juniors II | 0:0 | ||||
| 20. Jornada | 09.11.2021 | Huracán II | - | Argentinos Juniors II | 1:0 | ||||
| 21. Jornada | 18.11.2021 | Argentinos Juniors II | - | Godoy Cruz II | 1:1 | ||||
| 25. Jornada | 11.12.2021 | Argentinos Juniors II | - | Sarmiento de Junín II | 1:2 |
Argentina