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| 05.05.2018 | 00:00 | San Martín de San Juan | - | Vélez Sarsfield | 0:2 (0:2) | |
| 02:15 | San Lorenzo | - | Belgrano | 2:0 (1:0) | ||
| 18:15 | Argentinos Juniors | - | Godoy Cruz | 1:2 (1:1) | ||
| 18:15 | Arsenal de Sarandí | - | Rosario Central | 4:0 (3:0) | ||
| 20:30 | Newell's Old Boys | - | Defensa y Justicia | 1:0 (1:0) | ||
| 22:45 | Talleres de Córdoba | - | Huracán | 0:0 (0:0) | ||
| 06.05.2018 | 01:00 | Atlético Tucumán | - | Olimpo de Bahía Blanca | 1:1 (0:0) | |
| 16:00 | Temperley | - | Patronato de Paraná | 1:2 (0:2) | ||
| 18:15 | Independiente | - | Gimnasia de La Plata | 2:2 (1:1) | ||
| 20:30 | Tigre | - | CA Lanús | 0:0 (0:0) | ||
| 22:45 | Boca Juniors | - | Unión de Santa Fe | 2:0 (0:0) | ||
| 07.05.2018 | 01:00 | Estudiantes | - | Racing Club | 1:2 (0:1) | |
| 08.05.2018 | 00:00 | Banfield | - | Chacarita Juniors | 2:1 (1:1) | |
| 02:15 | Colón de Santa Fe | - | River Plate | 0:0 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Boca Juniors | 26 | 18 | 3 | 5 | 47:19 | 28 | 57 |
| 2 |
|
Godoy Cruz | 26 | 16 | 5 | 5 | 43:24 | 19 | 53 |
| 3 |
|
San Lorenzo | 26 | 14 | 8 | 4 | 31:18 | 13 | 50 |
| 4 |
|
Huracán | 26 | 13 | 8 | 5 | 32:21 | 11 | 47 |
| 5 |
|
Independiente | 26 | 13 | 7 | 6 | 29:18 | 11 | 46 |
| 6 |
|
Racing Club | 26 | 13 | 6 | 7 | 45:29 | 16 | 45 |
| 7 |
|
Talleres de Córdoba | 26 | 13 | 6 | 7 | 31:18 | 13 | 45 |
| 8 |
|
River Plate | 26 | 12 | 6 | 8 | 37:26 | 11 | 42 |
| 9 |
|
Defensa y Justicia | 26 | 12 | 5 | 9 | 39:34 | 5 | 41 |
| 10 |
|
Unión de Santa Fe | 26 | 10 | 10 | 6 | 32:23 | 9 | 40 |
| 11 |
|
Argentinos Juniors | 26 | 12 | 4 | 10 | 35:29 | 6 | 40 |
| 12 |
|
Belgrano | 26 | 10 | 10 | 6 | 27:25 | 2 | 40 |
| 13 |
|
Colón de Santa Fe | 26 | 10 | 8 | 8 | 29:21 | 8 | 38 |
| 14 |
|
Vélez Sarsfield | 26 | 10 | 7 | 9 | 30:31 | -1 | 37 |
| 15 |
|
Atlético Tucumán | 26 | 8 | 11 | 7 | 29:26 | 3 | 35 |
| 16 |
|
Estudiantes | 26 | 10 | 5 | 11 | 24:25 | -1 | 35 |
| 17 |
|
Banfield | 26 | 9 | 7 | 10 | 27:24 | 3 | 34 |
| 18 |
|
Patronato de Paraná | 26 | 8 | 8 | 10 | 26:32 | -6 | 32 |
| 19 |
|
Rosario Central | 26 | 8 | 7 | 11 | 29:40 | -11 | 31 |
| 20 |
|
San Martín de San Juan | 26 | 8 | 6 | 12 | 26:35 | -9 | 30 |
| 21 |
|
CA Lanús | 26 | 6 | 10 | 10 | 20:37 | -17 | 28 |
| 22 |
|
Newell's Old Boys | 26 | 8 | 6 | 12 | 23:26 | -3 | 27 |
| 23 |
|
Tigre | 26 | 4 | 12 | 10 | 26:31 | -5 | 24 |
| 24 |
|
Gimnasia de La Plata | 26 | 6 | 6 | 14 | 26:43 | -17 | 24 |
| 25 |
|
Temperley | 26 | 4 | 8 | 14 | 19:44 | -25 | 20 |
| 26 |
|
Chacarita Juniors | 26 | 4 | 6 | 16 | 22:36 | -14 | 18 |
| 27 |
|
Arsenal de Sarandí | 26 | 3 | 8 | 15 | 19:34 | -15 | 17 |
| 28 |
|
Olimpo de Bahía Blanca | 26 | 3 | 5 | 18 | 14:48 | -34 | 14 |
| Copa Libertadores | |
| Copa Sudamericana |
