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| 24.08.2022 | 19:30 | Juventud Unida de Gualeguaychú | - | Douglas Haig | 3:0 (1:0) | |
| 20:30 | Crucero del Norte | - | San Martín de Formosa | 3:1 (2:0) | ||
| 21:00 | Boca Unidos | - | Defensores Belgrano (VR) | 4:1 (1:1) | ||
| 25.08.2022 | 00:00 | Atlético Paraná | - | Unión de Sunchales | 2:1 (0:0) | |
| 01:00 | Sportivo Las Parejas | - | Defensores de Pronunciamiento | 0:0 (0:0) | ||
| 02:00 | Gimnasia y Esgrima (CdU) | - | Sarmiento de Resistencia | 0:1 (0:0) | ||
| 02:00 | Racing de Córdoba | - | Belgrano de San Francisco | 2:1 (1:1) | ||
| 03:15 | Juventud Antoniana | - | Central Norte | 1:0 (1:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Racing de Córdoba | 24 | 15 | 8 | 1 | 44:13 | 31 | 53 |
| 2 |
|
Sarmiento de Resistencia | 25 | 15 | 8 | 2 | 37:13 | 24 | 53 |
| 3 |
|
San Martín de Formosa | 24 | 13 | 5 | 6 | 44:26 | 18 | 44 |
| 4 |
|
Central Norte | 24 | 12 | 8 | 4 | 33:18 | 15 | 44 |
| 5 |
|
Gimnasia y Tiro de Salta | 24 | 11 | 5 | 8 | 22:25 | -3 | 38 |
| 6 |
|
Douglas Haig | 25 | 10 | 7 | 8 | 35:25 | 10 | 37 |
| 7 |
|
Belgrano de San Francisco | 25 | 10 | 5 | 10 | 34:30 | 4 | 35 |
| 8 |
|
Sportivo Las Parejas | 25 | 9 | 8 | 8 | 26:24 | 2 | 35 |
| 9 |
|
Gimnasia y Esgrima (CdU) | 24 | 10 | 5 | 9 | 26:25 | 1 | 35 |
| 10 |
|
Juventud Antoniana | 25 | 9 | 6 | 10 | 24:30 | -6 | 33 |
| 11 |
|
Crucero del Norte | 25 | 8 | 7 | 10 | 21:32 | -11 | 31 |
| 12 |
|
Boca Unidos | 24 | 5 | 10 | 9 | 23:27 | -4 | 25 |
| 13 |
|
Defensores Belgrano (VR) | 25 | 6 | 5 | 14 | 22:33 | -11 | 23 |
| 14 |
|
Atlético Paraná | 25 | 5 | 7 | 13 | 20:36 | -16 | 22 |
| 15 |
|
Defensores de Pronunciamiento | 24 | 4 | 9 | 11 | 15:31 | -16 | 21 |
| 16 |
|
Unión de Sunchales | 24 | 5 | 5 | 14 | 23:39 | -16 | 20 |
| 17 |
|
Juventud Unida de Gualeguaychú | 24 | 5 | 4 | 15 | 22:44 | -22 | 19 |
| Playoff |
