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| 08.01.2011 | 16:15 | AO Kavala | - | AE Lárissa | 1:0 (0:0) | |
| 18:30 | Panathinaikos | - | Aris Saloniki | 1:0 (1:0) | ||
| 09.01.2011 | 14:00 | Iraklis Saloniki | - | Atromitos | 1:0 (1:0) | |
| 14:00 | Panionios GSS | - | Skoda Xanthi | 0:2 (0:2) | ||
| 14:00 | Ergotelis | - | Olympiacos Volou | 0:0 (0:0) | ||
| 16:15 | Panserraikos | - | AEK Athen | 1:3 (1:2) | ||
| 16:15 | PAOK Saloniki | - | Asteras Tripolis | 1:0 (1:0) | ||
| 18:30 | AO Kerkyra | - | Olympiacos | 0:2 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Olympiacos | 17 | 14 | 0 | 3 | 33:7 | 26 | 42 |
| 2 |
|
Panathinaikos | 17 | 11 | 4 | 2 | 26:11 | 15 | 37 |
| 3 |
|
AEK Athen | 17 | 8 | 3 | 6 | 26:17 | 9 | 27 |
| 4 |
|
PAOK Saloniki | 17 | 8 | 3 | 6 | 18:17 | 1 | 27 |
| 5 |
|
AO Kavala | 17 | 6 | 6 | 5 | 16:14 | 2 | 24 |
| 6 |
|
Skoda Xanthi | 17 | 6 | 6 | 5 | 17:18 | -1 | 24 |
| 7 |
|
Aris Saloniki | 17 | 7 | 2 | 8 | 11:14 | -3 | 23 |
| 8 |
|
Olympiacos Volou | 17 | 4 | 10 | 3 | 16:15 | 1 | 22 |
| 9 |
|
Iraklis Saloniki | 17 | 5 | 7 | 5 | 14:15 | -1 | 22 |
| 10 |
|
Ergotelis | 17 | 6 | 3 | 8 | 16:22 | -6 | 21 |
| 11 |
|
AO Kerkyra | 17 | 5 | 5 | 7 | 14:20 | -6 | 20 |
| 12 |
|
Atromitos | 17 | 4 | 7 | 6 | 17:19 | -2 | 19 |
| 13 |
|
Asteras Tripolis | 17 | 4 | 7 | 6 | 13:15 | -2 | 19 |
| 14 |
|
Panserraikos | 17 | 4 | 4 | 9 | 14:24 | -10 | 16 |
| 15 |
|
Panionios GSS | 17 | 4 | 4 | 9 | 9:20 | -11 | 16 |
| 16 |
|
AE Lárissa | 17 | 2 | 5 | 10 | 10:22 | -12 | 11 |
| Champions League | |
| Playoff | |
| Descenso |
