 |
 |
|
|
| 11.02.2022 | 02:00 | Club León | - | CF América | 1:4 (1:0) | |
| 02:00 | UANL Tigres | - | Puebla FC | 2:0 (1:0) | ||
| 04:00 | Club Tijuana | - | CF Pachuca | 1:1 (1:0) | ||
| 12.02.2022 | 00:00 | Deportivo Toluca | - | CF Monterrey | 1:3 (1:1) | |
| 00:00 | Gallos Blancos | - | Mazatlán FC | 2:1 (0:1) | ||
| 19:00 | Pumas UNAM | - | Cruz Azul | 1:1 (1:0) | ||
| 19:00 | Atlas Guadalajara | - | Atlético San Luis | 1:1 (1:1) | ||
| 13.02.2022 | 17:30 | Deportivo Guadalajara | - | Santos Laguna | 1:0 (1:0) | |
| 20:45 | FC Juárez | - | Club Necaxa | 2:3 (2:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Monterrey | 7 | 7 | 0 | 0 | 23:4 | 19 | 21 |
| 2 |
|
UANL Tigres | 7 | 5 | 2 | 0 | 18:7 | 11 | 17 |
| 3 |
|
Deportivo Guadalajara | 7 | 5 | 2 | 0 | 14:4 | 10 | 17 |
| 4 |
|
CF América | 7 | 5 | 1 | 1 | 16:6 | 10 | 16 |
| 5 |
|
CF Pachuca | 7 | 5 | 1 | 1 | 15:8 | 7 | 16 |
| 6 |
|
Atlas Guadalajara | 7 | 2 | 4 | 1 | 7:9 | -2 | 10 |
| 7 |
|
Pumas UNAM | 7 | 2 | 2 | 3 | 8:8 | 0 | 8 |
| 8 |
|
Club Tijuana | 7 | 1 | 5 | 1 | 10:11 | -1 | 8 |
| 9 |
|
Cruz Azul | 7 | 2 | 2 | 3 | 6:8 | -2 | 8 |
| 10 |
|
Gallos Blancos | 7 | 2 | 2 | 3 | 7:12 | -5 | 8 |
| 11 |
|
Club Necaxa | 7 | 2 | 2 | 3 | 7:13 | -6 | 8 |
| 12 |
|
Atlético San Luis | 7 | 1 | 4 | 2 | 8:11 | -3 | 7 |
| 13 |
|
Club León | 7 | 2 | 1 | 4 | 10:15 | -5 | 7 |
| 14 |
|
Deportivo Toluca | 7 | 1 | 2 | 4 | 10:15 | -5 | 5 |
| 15 |
|
Mazatlán FC | 7 | 1 | 2 | 4 | 6:13 | -7 | 5 |
| 16 |
|
Puebla FC | 7 | 1 | 1 | 5 | 4:11 | -7 | 4 |
| 17 |
|
Santos Laguna | 7 | 1 | 1 | 5 | 4:12 | -8 | 4 |
| 18 |
|
FC Juárez | 7 | 1 | 0 | 6 | 8:14 | -6 | 3 |
| Playoff |
