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| 15.04.2016 | 18:00 | Mordovia Saransk | - | FK Amkar Perm | 1:1 (0:1) | |
| 16.04.2016 | 13:30 | Terek Grozny | - | FK Krasnodar | 0:1 (0:1) | |
| 16:00 | Lokomotiv Moskva | - | CSKA Moscú | 1:1 (1:0) | ||
| 18:30 | Zenit | - | Spartak Moskva | 5:2 (1:2) | ||
| 17.04.2016 | 13:30 | FK Ufa | - | Anzhi Makhachkala | 2:0 (1:0) | |
| 16:00 | Dinamo Moskva | - | Krylia Sovetov | 0:1 (0:0) | ||
| 18:30 | Kuban Krasnodar (1928-2018) | - | FK Rostov | 0:1 (0:0) | ||
| 18.04.2016 | 16:00 | FK Ural | - | Rubin Kazan | 0:1 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FK Rostov | 24 | 14 | 6 | 4 | 29:16 | 13 | 48 |
| 2 |
|
CSKA Moscú | 24 | 14 | 5 | 5 | 40:24 | 16 | 47 |
| 3 |
|
Zenit | 24 | 13 | 7 | 4 | 49:27 | 22 | 46 |
| 4 |
|
FK Krasnodar | 24 | 12 | 7 | 5 | 42:22 | 20 | 43 |
| 5 |
|
Lokomotiv Moskva | 24 | 12 | 7 | 5 | 37:27 | 10 | 43 |
| 6 |
|
Terek Grozny | 24 | 9 | 11 | 4 | 32:23 | 9 | 38 |
| 7 |
|
Spartak Moskva | 24 | 11 | 4 | 9 | 36:34 | 2 | 37 |
| 8 |
|
FK Ural | 24 | 9 | 7 | 8 | 35:39 | -4 | 34 |
| 9 |
|
Rubin Kazan | 24 | 9 | 3 | 12 | 29:32 | -3 | 30 |
| 10 |
|
FK Amkar Perm | 24 | 6 | 8 | 10 | 20:28 | -8 | 26 |
| 11 |
|
Krylia Sovetov | 24 | 7 | 5 | 12 | 15:26 | -11 | 26 |
| 12 |
|
Dinamo Moskva | 24 | 5 | 9 | 10 | 24:36 | -12 | 24 |
| 13 |
|
FK Ufa | 24 | 5 | 8 | 11 | 20:33 | -13 | 23 |
| 14 |
|
Kuban Krasnodar (1928-2018) | 24 | 3 | 11 | 10 | 30:35 | -5 | 20 |
| 15 |
|
Mordovia Saransk | 24 | 2 | 11 | 11 | 24:37 | -13 | 17 |
| 16 |
|
Anzhi Makhachkala | 24 | 3 | 7 | 14 | 22:45 | -23 | 16 |
| Champions League | |
| CL Ronda previa | |
| Europa League | |
| EL Ronda previa | |
| Permanencia | |
| Descenso |
