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| 08.04.2022 | 11:00 | Krylia Sovetov | - | FK Chertanovo | 0:2 (0:1) | |
| 12:00 | Dinamo Moskva | - | FK Rostov | 1:4 (0:2) | ||
| 12:00 | Rubin Kazan | - | Zenit St. Petersburg | 1:2 (0:1) | ||
| 13:00 | Spartak Moskva | - | PFC Sochi | 1:0 (0:0) | ||
| 18:00 | CSKA Moskva | - | Lokomotiv Moskva | 2:1 (2:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª parte | 2.ª parte |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CSKA Moskva | 22 | 17 | 1 | 4 | 49:18 | 31 | 52 |
| 2 |
|
FK Rostov | 22 | 16 | 2 | 4 | 57:20 | 37 | 50 |
| 3 |
|
Lokomotiv Moskva | 22 | 13 | 4 | 5 | 38:23 | 15 | 43 |
| 4 |
|
Zenit St. Petersburg | 22 | 13 | 1 | 8 | 53:30 | 23 | 40 |
| 5 |
|
Dinamo Moskva | 22 | 13 | 1 | 8 | 44:34 | 10 | 40 |
| 6 |
|
Spartak Moskva | 22 | 12 | 3 | 7 | 35:22 | 13 | 39 |
| 7 |
|
FK Chertanovo | 22 | 11 | 4 | 7 | 36:27 | 9 | 37 |
| 8 |
|
Krylia Sovetov | 22 | 11 | 3 | 8 | 28:34 | -6 | 36 |
| 9 |
|
PFC Sochi | 22 | 11 | 1 | 10 | 35:35 | 0 | 34 |
| 10 |
|
Rubin Kazan | 22 | 9 | 6 | 7 | 44:35 | 9 | 33 |
