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| 01.04.2022 | 12:00 | Lokomotiv Moskva | - | Krylia Sovetov | 4:1 (0:1) | |
| 12:00 | FK Chertanovo | - | Rubin Kazan | 1:2 (1:0) | ||
| 13:00 | Zenit St. Petersburg | - | Dinamo Moskva | 1:0 (0:0) | ||
| 15:00 | PFC Sochi | - | CSKA Moskva | 1:3 (1:1) | ||
| 15:30 | FK Rostov | - | Spartak Moskva | 0:1 (0:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª parte | 2.ª parte |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CSKA Moskva | 21 | 16 | 1 | 4 | 47:17 | 30 | 49 |
| 2 |
|
FK Rostov | 21 | 15 | 2 | 4 | 53:19 | 34 | 47 |
| 3 |
|
Lokomotiv Moskva | 21 | 13 | 4 | 4 | 37:21 | 16 | 43 |
| 4 |
|
Dinamo Moskva | 21 | 13 | 1 | 7 | 43:30 | 13 | 40 |
| 5 |
|
Zenit St. Petersburg | 21 | 12 | 1 | 8 | 51:29 | 22 | 37 |
| 6 |
|
Spartak Moskva | 21 | 11 | 3 | 7 | 34:22 | 12 | 36 |
| 7 |
|
Krylia Sovetov | 21 | 11 | 3 | 7 | 28:32 | -4 | 36 |
| 8 |
|
FK Chertanovo | 21 | 10 | 4 | 7 | 34:27 | 7 | 34 |
| 9 |
|
PFC Sochi | 21 | 11 | 1 | 9 | 35:34 | 1 | 34 |
| 10 |
|
Rubin Kazan | 21 | 9 | 6 | 6 | 43:33 | 10 | 33 |
