| 1. Jornada | 17.07.2021 | CA Lanús | - | Atlético Tucumán | 4:2 |  |
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| 11. Jornada | 14.09.2021 | Central Córdoba SdE | - | Atlético Tucumán | 2:0 | |
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| 12. Jornada | 19.09.2021 | Atlético Tucumán | - | Boca Juniors | 1:2 | ||||
| 14. Jornada | 02.10.2021 | Atlético Tucumán | - | San Lorenzo | 0:0 | ||||
| 17. Jornada | 21.10.2021 | Estudiantes | - | Atlético Tucumán | 1:1 | ||||
| 18. Jornada | 25.10.2021 | Atlético Tucumán | - | Patronato de Paraná | 2:2 | ||||
| 20. Jornada | 07.11.2021 | Atlético Tucumán | - | Racing Club | 0:2 | |
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| 22. Jornada | 24.11.2021 | Atlético Tucumán | - | Defensa y Justicia | 0:4 | |
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| 23. Jornada | 29.11.2021 | Unión de Santa Fe | - | Atlético Tucumán | 3:0 | |
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| 24. Jornada | 03.12.2021 | Colón de Santa Fe | - | Atlético Tucumán | 3:0 | ||||
| 25. Jornada | 11.12.2021 | Atlético Tucumán | - | River Plate | 1:1 |
Argentina